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. 2018 Mar 6;9:70. doi: 10.3389/fendo.2018.00070

Table 1.

Overview of recently completed, current and planned clinical trials aimed at prevention of type 1 diabetes.

Recently completed Trial to Reduce IDDM in the Genetically at Risk (TRIGR)
BABYDIET study in Germany
Finnish Dietary Intervention Trial for the Prevention of Type 1 Diabetes (FINDIA)
TrialNet Nutritional Intervention to Prevent (NIP) Type 1 diabetes study
Type 1 Diabetes Prediction and Prevention (DIPP) study in Finland
Pre-POINT (Primary Oral/Intranasal INsulin Trial) and Pre-POINT-early in Germany
Diabetes Prevention Trial-Type 1 (DPT-1)
TrialNet Oral Insulin study
Australian Intranasal Insulin Trial-I (INIT I)
Diabetes Prevention—Immune Tolerance (DIAPREV-IT) study
European Nicotinamide Diabetes Intervention Trial

Current TrialNet Teplizumab (anti-CD3) trial
TrialNet Abatacept (CTLA4-Ig) trial
The CoRD Study with autologous cord blood in Australia
DIAPREV-IT2 study
Australian Intranasal Insulin Trial-II (INIT II)

Future TrialNet Aldomet (methyldopa) study
TrialNet Hydroxychloriquine
TrialNet Rituximab and Abatacept
Fr1da Insulin Intervention in Germany
Adjunctive therapies such as glucagon-like peptide-1 receptor agonists