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. 2018 Mar 6;9:185. doi: 10.3389/fphys.2018.00185

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Copyright © 2018 Astorga, González-Candia, Candia, Figueroa, Cañas, Ebensperger, Reyes, Llanos and Herrera.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pulmonary nitrosative stress. Representative micrographs (40x) of pulmonary resistance arteries (A) and nitrotyrosine intensity in pulmonary resistance arteries (B). Representative micrographs (40x) of pulmonary trunk (C) and nitrotyrosine intensity in pulmonary trunk (D). Groups are control (CN, open bars, n = 6) and melatonin treated (MN, closed bars, n = 6) lambs. Values are means ± SEM. Significant differences (P ≤ 0.05): ^*vs. CN. Scale bar: 100 μm.