Table 3.
Results of the subtests of the neuropsychological evaluation selected for the assessment of executive (TMT) and working memory functions (digit span) in the control sample and in the HD group.
| Controls | Manifest HD | Pre-HD | |
|---|---|---|---|
| TMT A (sec) | 35 ± 10 | 63.7 ± 24.3a | 32.4 ± 11.2 |
| TMT B (sec) | 82.9 ± 41.8 | 258.7 ± 206.5a | 65.9 ± 39.3 |
| TMT B–A (sec) | 47.9 ± 40.9 | 194.9 ± 184.4a | 33.4 ± 33 |
| Digit span forward | 6.6 ± 1.1 | 4.32 ± 1.3a | 5.7 ± 1.1 |
| Digit span backward | 4.9 ± 1.1 | 3 ± 0.7a | 4.6 ± 1.1 |
| Digit span forward–backward | 1.6 ± 1.3 | 1.6 ± 0.6 | 1.1 ± 0.9 |
a
Significant differences between manifest patients and controls (p < .05). Values are given in means ± SD; TMT = Trail Making Test.