Table 2.

Physiological and biochemical parameters of the ALF and control mice.

Parameters	Control (n = 6)	ALF (n = 6)
Liver weight/body weight (%)	3.1 ± 0.1	4.5 ± 0.2*
ALT (units/L)	38.6 ± 10.7	192.4 ± 33.1**
AST (units/L)	26.4 ± 8.6	349.2 ± 72.4**
ALP (units/L)	246.4 ± 33.7	619.4 ± 118.1**
Total bilirubin (μmol/L)	5.4 ± 1.4	24.6 ± 6.6**
Conjugated bilirubin (μmol/L)	3.1 ± 0.8	15.5 ± 4.3**
Total bile acids (μmol/L)	32.7 ± 9.6	113.4 ± 27.9**
Ammonia (μmol/L)	76.7 ± 14.2	86.1 ± 17.8
TNF-α (pg/mL)	6.7 ± 2.5	47.5 ± 10.7**
NO (brain) (μM/g)	13.5 ± 4.0	12.1 ± 3.9
GSH (brain) (μM/g)	3.5 ± 1.4	1.8 ± 0.8*
MDA (brain) (mmol/g)	33.7 ± 7.2	75.3 ± 15.3**
SOD (brain) (units/mg protein)	7.7 ± 2.2	5.9 ± 2.8
CAT (brain) (units/mg protein)	18.4 ± 4.0	11.4 ± 4.1**

Data are expressed as mean ± SD (n = 6). ^∗P < 0.05, ^∗∗P < 0.01 vs. control.