Figure 2.

Therapeutic properties of multipotent mesenchymal stromal cells. MSCs have emerged as a promising cell therapy for inflammatory/autoimmune diseases and in regenerative medicine due to their (i) secretion of trophic factors that promote a regenerative microenvironment, (ii) their capacity to differentiate into adipocytes, osteoblasts, and chondroblasts in vitro and in vivo and (iii) their immunomodulatory capacity where MSCs can inhibit the activation of T cells, NK cells, and B cells, prevent the maturation of dendritic cells (iDC) and promote immunological tolerance through the induction of M2 macrophages and regulatory T cells (Tregs).