Table 1.
Complete TCRγδ+ T-LGL leukemia receptor clonotypes identified in the repertoire of healthy young and elderly individuals.
| Sample information |
LGL sample | TRG receptor chain |
TRD receptor chain |
|||||
|---|---|---|---|---|---|---|---|---|
| Donor | Sex | Age | Subset | V-J rearrangement | CDR3 composition | V-J rearrangement | CDR3 composition | |
| Young individuals | ||||||||
| B49 | F | 26 | Naive | LGL 12-098 | Vδ3–Jδ1 | CAFSSLTGGYKEYTDKLIF | Vγ9–Jγ1.3 | CALWEVPNYKKLF |
| Elderly individuals | ||||||||
| B41 | M | 56 | Naive | LGL 10-200 | Vδ2–Jδ1 | CACDTVGDRDTDKLIF | Vγ9–Jγ1.3 | CALWEVQYYKKLF |
| LGL 12-098 | Vδ3–Jδ1 | CAFSSLTGGYKEYTDKLIF | Vγ9–Jγ1.3 | CALWEVPNYKKLF | ||||
| B51 | M | 70 | Effector | LGL 10-200 | Vδ2–Jδ1 | CACDTVGDRDTDKLIF | Vγ9–Jγ1.3 | CALWEVQYYKKLF |
| B44 | F | 69 | Effector | LGL 12-098 | Vδ3–Jδ1 | CAFSSLTGGYKEYTDKLIF | Vγ9–Jγ1.3 | CALWEVPNYKKLF |
| B60 | M | 68 | Effector | LGL 12-098 | Vδ3–Jδ1 | CAFSSLTGGYKEYTDKLIF | Vγ9–Jγ1.3 | CALWEVPNYKKLF |