Table 1.
Subjects demographics and trauma history.
| CLES = 0 | CLES =1 | CLES ≥ 2 | Total | |
|---|---|---|---|---|
| Males | ||||
| AAO ≤ 18 | 98 | 38 | 61 | 197 |
| AAO > 18 | 109 | 46 | 55 | 210 |
| Total | 207 | 84 | 116 | 407 |
| Females | ||||
| AAO ≤ 18 | 147 | 99 | 161 | 407 |
| AAO > 18 | 126 | 93 | 86 | 305 |
| Total | 273 | 192 | 247 | 712 |
| Combined | ||||
| AAO ≤ 18 | 245 | 137 | 222 | 604 |
| AAO > 18 | 235 | 139 | 141 | 515 |
| Total | 480 | 276 | 363 | 1119 |
Note: GWAS SNP genotypes in all subjects with AAO ≥ 12 were tested for interaction effect upon AAO with CLES as a continuous measure (n = 1119) and classified as CLES = 0 versus CLES ≥ 2 (combined n= 843). GWAS: Genome-wide association study; AAO: Age at onset; CLES: Childhood Life Events Scale.