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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Toxicology. 2018 Feb 7;396-397:54–67. doi: 10.1016/j.tox.2018.02.004

Figure 10. Percentage of CD86+ monocyte/macrophage/granulocytes post LPS activation by treatment group and sex.

Figure 10

Male rats were administrated vehicle (VH, 0.3% aqueous carboxymethylcellulose), BPA or estrogen ethinyl estradiol (EE2) at the indicated dose level by oral gavage daily and sacrificed at postnatal day (PND) 6 months (A) and 1 year (B). Splenocytes were isolated and treated with LPS for up to 48 h. The percentage of CD86+ cells within CD172a+ monocyte/macrophage/granulocytes was quantified by flow cytometry. Results are presented as mean ± SE. n = 2–10 rats/treatment group/sex, n = 2 rats in PND 1 year 250μg BPA/kg/day male groups. * p < 0.05 when compared to respective vehicle control by a two way ANOVA with Dunnett’s posttest.