Table 4.
Effects of EE2 and BPA on NK cell activation at 24 or 48 hr after LPS stimulation.
| PND 6 Month | PND 1 Year | |||||
|---|---|---|---|---|---|---|
|
|
|
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| Endpoints | Time points | Sex | EE2 | BPA | EE2 | BPA |
| % CD80+ cells within NK cells | 24hr | F | ↓0.5 | ↓25000 | N | N |
| M | ↑0.5 | ↑2.5 | N | N | ||
|
| ||||||
| 48hr | F | N | N | N | N | |
| M | N | N | N | N | ||
|
| ||||||
| % CD86+ cells within NK cells | 24hr | F | N | N | N | N |
| M | N | ↑25000 | N | ↑25000 | ||
|
| ||||||
| 48hr | F | N | N | N | N | |
| M | N | N | N | ↑25 | ||
F: female; M: male. N indicates no significant difference compared to control groups. ↑ indicates increase and ↓ indicates decrease. Numbers designate the dose levels (μg/kg bw/day) at which significant changes were observed.