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. Author manuscript; available in PMC: 2018 Mar 12.
Published in final edited form as: Contraception. 2013 Aug 14;88(6):749–757. doi: 10.1016/j.contraception.2013.08.003

Table 2.

Predicted sensitivities of detecting biomarkera by semen dose and time since exposure

Semen dosec Time postexposure Biomarker
Difference (Yc DNA −PSA) 95% CI
PSA
Yc DNA
Prob 95% CI Prob 95% CI
10 μL   0 h 0.49 0.35, 0.63 0.62 0.47, 0.75   0.13 −0.12, 0.28
  1 h 0.24 0.14, 0.39 0.40 0.27, 0.55   0.16b   0.02, 0.29
  6 h 0.11 0.05, 0.24 0.38 0.25, 0.53   0.27b   0.11, 0.42
12 h 0.04 0.01, 0.16 0.24 0.14, 0.39   0.20b   0.07, 0.33
  1 day 0.04 0.01, 0.16 0.18 0.09, 0.32   0.14b   0.02, 0.25
  2 days 0.07 0.02, 0.19 0.22 0.12, 0.37   0.15b   0.03, 0.28
  3 days 0.04 0.01, 0.16 0.11 0.05, 0.24   0.07 −0.03, 0.16
  6 days 0.02 0.00, 0.15 0.02 0.00, 0.15   0.00 −0.06, 0.06
100 μL   0 h 0.89 0.77, 0.96 0.72 0.58, 0.83 −0.17b −0.29, −0.05
  1 h 0.81 0.66, 0.90 0.68 0.53, 0.80 −0.13 −0.30, 0.04
  6 h 0.37 0.24, 0.52 0.63 0.48, 0.76   0.26b   0.09, 0.44
12 h 0.24 0.14, 0.39 0.59 0.44, 0.72   0.35b   0.19, 0.51
  1 day 0.11 0.05, 0.24 0.41 0.28, 0.56   0.30b   0.16, 0.45
  2 days 0.02 0.00, 0.14 0.26 0.15, 0.41   0.24b   0.12, 0.36
  3 days 0.07 0.02, 0.19 0.15 0.07, 0.29   0.08 −0.05, 0.22
  6 days 0.04 0.01, 0.16 0.04 0.01, 0.16   0.00 −0.09, 0.09
1000 μL   0 h 0.96 0.83, 0.99 0.72 0.57, 0.83 −0.24b −0.39, −0.08
  1 h 0.86 0.72, 0.94 0.76 0.61, 0.87 −0.10 −0.24, 0.05
  6 h 0.65 0.50, 0.78 0.60 0.45, 0.74 −0.05 −0.25, 0.13
12 h 0.44 0.30, 0.59 0.63 0.48, 0.76   0.19 −0.02, 0.39
  1 day 0.21 0.11, 0.36 0.49 0.34, 0.64   0.28b   0.12, 0.44
  2 days 0.07 0.02, 0.20 0.21 0.11, 0.36   0.14b   0.01, 0.28
  3 days 0.07 0.02, 0.20 0.17 0.09, 0.32   0.10 −0.03, 0.22
  6 days 0.09 0.04, 0.23 0.12 0.05, 0.25   0.03 −0.08, 0.12

Prob=predicted sensitivity.

a

Positive PSA result defined as ≥1 ng/mL, and positive Yc DNA result defined as >0 ng/mL (detection of any Yc DNA).

b

Significant at p=.05 level.

c

The 10-μL cycle includes samples from 45 couples, the 100-μL cycle includes samples from 46 couples, and the 1000-μL cycle includes samples from 43 couples.