Table 2.
Frequency of transduced cells by cell type, vector, and spinal cord region in samples harvested at postnatal month 7.
| IDLV-CMV-GFP-VSV-G | IDLV-CMV-GFP-Rabies | scAAV9-CAG-GFP | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | GFP +/ChAT + | Total ChAT + | % | N | GFP +/ChAT + | Total ChAT + | % | N | GFP +/ChAT + | Total ChAT + | % | |
| Cervical | 3 | 243 | 243 | 100 | 3 | 222 | 222 | 100 | 3 | 93 | 266 | 34.9 ± 7 |
| Thoracic | 3 | 133 | 133 | 100 | 3 | 131 | 131 | 100 | 3 | 71 | 220 | 32.2 ± 4 |
| Lumbar | 3 | 259 | 259 | 100 | 3 | 227 | 227 | 100 | 3 | 107 | 264 | 40.5 ± 4 |
| N | GFP +/NeuN + | Total NeuN + | % | N | GFP +/NeuN + | Total NeuN + | % | N | GFP +/NeuN + | Total NeuN + | % | |
| Cervical | 3 | 63 | 455 | 13.8 ± 6 | 3 | 166 | 461 | 36.1 ± 3 | 3 | 67 | 423 | 15.8 ± 5 |
| Thoracic | 3 | 71 | 443 | 16.1 ± 5 | 3 | 148 | 417 | 35.4 ± 4 | 3 | 49 | 395 | 12.4 ± 3 |
| Lumbar | 3 | 83 | 496 | 16.7 ± 6 | 3 | 149 | 441 | 34.7 ± 7 | 3 | 77 | 463 | 16.6 ± 5 |