Table 2.
Day | Logarithm of counted colony numbers (log10 CFU/mL)
|
|||||
---|---|---|---|---|---|---|
2 | 4 | 6 | 8 | 10 | ||
Control | H37Rv | 5.74±0.05 | 5.96±0.07 | 6.48±0.03 | 6.76±0.1 | 6.90±0.03 |
H37RvΔmazEF3 | 572±0.04 | 5.94±0.07 | 6.44±0.04 | 6.72±0.4 | 6.86±0.05 | |
H37RvΔmazEF6 | 5.71±0.03 | 5.91±0.04 | 6.43±0.04 | 6.7±0.03 | 6.84±0.04 | |
H37RvΔmazEF9 | 5.72±0.03 | 5.91±0.03 | 6.44±0.02 | 6.71±0.03 | 6.87±0.04 | |
Compare result | F=0.361 | F=0.578 | F=1.07 | F=0.679 | F=0.869 | |
P>0.05 | P>0.05 | P>0.05 | P>0.05 | P>0.05 | ||
Hypoxia | H37Rv | 5.27±0.06 | 5.81±0.05 | 5.61±0.09 | 5.1±0.03 | 4.69±0.09 |
H37RvΔmazEF3 | 5.22±0.04 | 6.77±0.02 | 5.55±0.06 | 5.06±0.03 | 4.42±0.03 | |
H37RvΔmazEF6 | 5.23±0.06 | 5.75±0.04 | 5.53±0.05 | 5.03±0.05 | 4.4±0.03 | |
H37RvΔmazEF9 | 5.21±0.04 | 5.76±0.03 | 5.54±0.03 | 5.04±0.03 | 4.41±0.03 | |
Compare result | F=0.716 | F=1.645 | F=1.014 | F=2.207 | F=22.849 | |
P>0.05 | P>0.05 | P>0.05 | P>0.05 | P<0.01 | ||
Nutrient starvation | H37Rv | 4.6±0.06 | 4.35±0.06 | 4.15±0.07 | 4.07±0.05 | 3.62±0.1 |
H37RvΔmazEF3 | 4.53±0.02 | 4.32±0.06 | 4.11±0.07 | 3.84±0.03 | 3.41±0.02 | |
H37RvΔmazEF6 | 4.52±0.035 | 4.27±0.061 | 4.09±0.087 | 3.78±0.04 | 3.37±0.031 | |
H37RvΔmazEF9 | 4.54±0.051 | 4.28±0.082 | 4.1±0.053 | 3.81±0.03 | 3.39±0.032 | |
Compare result | F=2.141 | F=0.904 | F=138.179 | F=40.388 | F=426.488 | |
P>0.05 | P>0.05 | P<0.01 | P<0.01 | P<0.01 |
Notes: Three deletion strains compared with H37Rv in various growth conditions. Data presented as mean ± SD.