Figure 2.

The expression of ING3 is a poor prognostic marker for PC patients. (A) Prostate tissue microarray (TMA) were stained for ING3 by immunohistochemistry (B) TMA were scored for positive staining (histoscore or H-score). Data represent H-score for ING3 staining of PC (n=81) samples and BPH (n=41) samples. ***P<0.001. (C) ING3 H-scores comparison between castration sensitive (n=14) and castrate-resistant prostate cancer (CRPC) patients (n=9). (D) Kaplan–Meier overall survival curve based on patients with low (n=35) or high (n=55) ING3 protein levels (*P-value of 0.03). All error bars represent the s.e.m. BPH=benign prostatic hyperplasia; ING=INhibitor of Growth; PC=prostate cancer.