Figure 5.

Analysis of patient-derived CaP xenograft samples. (A) The expression of BMP6, ROR2, and CCL2 was analysed in tumours from PCSD1 bone-niche model. PCR was repeated at least three times. (B) and a single-picture representative of IF demonstrated that high expression of CCL2 with high-Gleason tumour as compared with low-Gleason tumour. Macrophage infiltration also little bit higher in high-Gleason tumour than low-Gleason tumour. *P < 0.05. BMP6=bone morphogenetic protein 6; CCL2=chemokine ligand 2.