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. Author manuscript; available in PMC: 2018 May 24.
Published in final edited form as: Sci Transl Med. 2017 May 24;9(391):eaal3226. doi: 10.1126/scitranslmed.aal3226

Table 1. Summary of patient cohorts.

Characteristic Training cohort Prospective Cohort Total
Malignant Benign Malignant Benign
Total cases 22 10 82 21 135

Subtypes

  PDAC untreated 13 - 22 - 35

  PDAC neoadjuvant tx 9 - 24 - 33

  IPMN inter/high grade - - 13 - 13

  NET - - 12 - 12

  Other cancer - - 11 - 11

  Benign cystic tumor - - - 5 5

  Pancreatitis - - - 8 8

  Controls - 10 - 8 18

Age

  Median 68 48 65 57 63

  Range 47–88 23–82 17–84 19–91 17–91

Sex

  Male 8 4 47 14 73

  Female 14 1 40 14 69

CA19-9

  PDAC untreated 1148 (1–6684) - 1,006 (1–10,625) - 1064 (1–10,625)

  PDAC neoadjuvant tx 2258 (19–17,101) - 657 (4–7,730) - 1175 (4–17,101)

  IPMN - - 10.6 (1–26) - 10.6 (1–26)

CEA

  PDAC untreated 7.0 (2–12) - 3.4 (0.6–22.1) - 5.0 (0.6–22.1)

  PDAC neoadjuvant tx 11.0 (1–53) - 56.4 (0.7–1003) - 40 (0.7–1003)

  IPMN - - 2.1 (0.7–3.3) - 2.1 (0.7–3.3)

Stage

  I 0 - 10 - 10

  II 1 - 42 - 43

  III 5 - 5 - 10

  IV 16 - 10 - 26

Co-therapies PDAC

  Folforinox/XRT 4 - 21 - 25

  Gemcitabine 5 - 1 - 6

  Other - - 2 - 2