Table 2. Antiproliferative Effects against Prostate Cell Lines C4-2B, LNCaP, 22Rv1, PC3, and Du145.
cell
growth inhibition (IC50, μM)a |
|||||
---|---|---|---|---|---|
compd | C4-2B | LNCaP | 22Rv1 | PC-3 | Du145 |
1 | 0.19 | 0.16 | 0.071 | 3.01 | 2.52 |
15 | 7.04 | 8.40 | 8.02 | 30.40 | 35.93 |
17 | 13.26 | 7.52 | 13.08 | 40.13 | 92.56 |
23 | 7.16 | 7.80 | 7.05 | 26.95 | 54.50 |
25 | 6.56 | 6.28 | 4.85 | 21.01 | 30.93 |
36 | 3.23 | 4.41 | 3.38 | 17.22 | 23.19 |
37 | 7.75 | 7.70 | 7.59 | 22.85 | 33.24 |
The IC50 was calculated from cell viability assay by Cell-Titer GLO (Promega).