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. 2018 Feb 13;9(3):262–267. doi: 10.1021/acsmedchemlett.8b00003

Table 2. Antiproliferative Effects against Prostate Cell Lines C4-2B, LNCaP, 22Rv1, PC3, and Du145.

  cell growth inhibition (IC50, μM)a
compd C4-2B LNCaP 22Rv1 PC-3 Du145
1 0.19 0.16 0.071 3.01 2.52
15 7.04 8.40 8.02 30.40 35.93
17 13.26 7.52 13.08 40.13 92.56
23 7.16 7.80 7.05 26.95 54.50
25 6.56 6.28 4.85 21.01 30.93
36 3.23 4.41 3.38 17.22 23.19
37 7.75 7.70 7.59 22.85 33.24
a

The IC50 was calculated from cell viability assay by Cell-Titer GLO (Promega).