Table 4.
HR and 95% CI for Joint Associations of Amount of Walking/Jogging/Running and Intensity with Digestive System Cancers
| Walking/Jogging/Running (median, MET-hours/week)a
|
||||
|---|---|---|---|---|
| < 3 | 3+ | |||
|
|
||||
| Reference (1.0) | Q1 (5.4) | Q2 (13.5) | Q3 (31.5) | |
|
Average METb
|
||||
| ≤ 4.5 | ||||
| No. of incident cases (person-years) | 291(140,093) | 251(113,428) | 196(80,015) | |
| Multivariablec | 0.85(0.72,1.00) | 0.80(0.67,0.95) | 0.79(0.66,0.95) | |
| Multivariable+BMI+DMd | 324(140,748) | 0.86(0.73,1.01) | 0.82(0.69,0.97) | 0.82(0.68,0.99) |
| 1 (reference) | ||||
| > 4.5 | 1 (reference) | |||
| No. of incident cases (person-years) | 37(28,916) | 78(57,662) | 123(90,782) | |
| Multivariablec | 0.76(0.54,1.07) | 0.83(0.64,1.07) | 0.80(0.64,0.99) | |
| Multivariable+BMI+DMd | 0.79(0.56,1.11) | 0.87(0.67,1.12) | 0.85(0.69,1.06) | |
a
The cut-off for the reference group was chosen to represent the minimal among multiples of 3 MET-hours/week; non-reference group was categorized based on tertiles to balance data across joint categories, which helps obtain reliable estimates.
b
Weighted average of MET values of walking (at normal, brisk, or very brisk pace), jogging, and running using weekly hours spent for each activity as the weight
c
Multivariable analyses were adjusted for the same set of variables as denoted in Table 2
d
Multivariable analyses were adjusted for the same set of variables as denoted in Table 2