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. 2018 Feb 15;62:10.29219/fnr.v62.1285. doi: 10.29219/fnr.v62.1285

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© 2018 Dan-Dan Wang et al.

This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for any purpose, even commercially, provided the original work is properly cited and states its license.

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Fig. 4 — The multicellular spheroids of Hela cells were treated with 5-Fu (25 μg/mL) and SAP (200 μg/mL). (a) Cellular morphological changes during 4 days of culture in 3D constructs were observed under contrast microscope (Olympus, Japan). (b) Representative photographs of the multicellular spheroids and (c) distribution of spheroid diameter in 3D Hela cells on day 6.