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. Author manuscript; available in PMC: 2018 Apr 19.
Published in final edited form as: Bioconjug Chem. 2017 Mar 17;28(4):880–884. doi: 10.1021/acs.bioconjchem.7b00057

Figure 2.

Figure 2

a) Strategy to deliver CRISPR/Cas9 components through viral delivery. b) AAV8-CRISPR delivery into Duchenne muscular dystrophy mice (mdx) to correct mutated dystrophin gene resulted restoration of dystrophin protein. Reprinted with permission from ref 19. Copyright 2016 Nature Publishing Group.