Table 3.

Three‐month confirmed disability progression (composite endpoint) by baseline normalized brain volume category

Baseline normalized brain volume category	Incidence of disability progression over 3 years, %a (95% CI)	Risk of disability progression compared with low normalized brain volume categoryb
		Risk reduction, %	HR (95% CI)	P
Low (n = 70)	90.8 (82.9; 98.7)
Expected (n = 351)	73.8 (68.9; 78.8)	24.30	0.76 (0.56; 1.02)	0.0647
High (n = 61)	66.7 (53.8; 79.5)	36.47	0.64 (0.42; 0.97)	0.0339

^aKaplan–Meier estimate.

^bCox model.