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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Obesity (Silver Spring). 2017 Sep 18;25(11):1997–2008. doi: 10.1002/oby.22000

Table 3.

Risk for developing hypertension and diabetes mellitus.

Total (n=9,721) Hypertension
Diabetes mellitus
Crude
Adjusted*
Crude
Adjusted*
OR 95% CI p OR 95% CI P OR 95% CI P OR 95% CI P
Lean/normal without MetS Reference Reference Reference Reference
Overweight/obesity without MetS 2.19 1.80–2.67 <0.001 1.93 1.57–2.38 <0.001 2.48 1.58–3.90 <0.001 1.94 1.22–3.10 0.005
Lean/normal with MetS 5.00 3.91–6.38 <0.001 3.53 2.75–4.55 <0.001 7.18 4.57–11.3 <0.001 4.68 2.93–7.46 <0.001
Overweight/obesity with MetS 5.10 4.10–6.35 <0.001 4.27 3.38–5.39 <0.001 9.78 6.80–14.3 <0.001 7.10 4.74–10.6 <0.001
Hyperuricemia 2.10 1.78–2.47 <0.001 1.36 1.13–1.63 0.001 2.64 1.89–3.68 <0.001 1.38 0.96–1.99 0.080
Serum uric acid (per 1 mg/dL increased) 1.36 1.30–1.43 <0.001 1.19 1.11–1.27 <0.001 1.55 1.40–1.72 <0.001 1.27 1.10–1.45 <0.001
Sex (men) 1.92 1.68–2.20 <0.001 1.31 1.10–1.55 0.002 2.84 2.07–3.90 <0.001 1.89 1.28–2.78 0.001

Men (n=4,160)
Lean/normal without MetS Reference Reference Reference Reference
Overweight/obesity without MetS 1.54 1.21–1.96 <0.001 1.60 1.25–2.06 <0.001 1.64 0.98–2.76 0.062 1.71 1.005–2.90 0.048
Lean/normal with MetS 3.59 2.52–5.11 <0.001 3.00 2.10–4.31 <0.001 4.45 2.38–8.33 <0.001 3.36 2.54–14.5 <0.001
Overweight/obesity with MetS 3.24 2.49–4.22 <0.001 3.43 2.61–4.52 <0.001 5.70 3.65–8.89 <0.001 5.86 0.090–5.96 <0.001
Hyperuricemia 1.38 1.13–1.69 0.002 1.24 1.002–1.53 0.048 1.56 1.06–2.30 0.025 1.24 0.82–1.88 0.30
Serum uric acid (per 1 mg/dL increased) 1.70 1.53–1.90 <0.001 1.12 1.03–1.21 0.006 1.30 1.12–1.51 <0.001 1.21 1.03–1.43 0.017

Women (n=5,561)
Lean/normal without MetS Reference Reference Reference Reference
Overweight/obesity without MetS 2.83 1.99–4.03 <0.001 2.71 1.89–3.90 <0.001 2.89 1.11–7.50 0.029 2.38 0.91–6.23 0.077
Lean/normal with MetS 6.46 4.61–9.07 <0.001 3.91 2.74–5.59 <0.001 11.8 6.06–23.0 <0.001 6.56 3.24–13.3 <0.001
Overweight/obesity with MetS 8.84 5.84–13.4 <0.001 6.28 4.01–9.78 <0.001 16.6 7.91–34.9 <0.001 9.46 4.21–21.3 <0.001
Hyperuricemia 3.25 2.37–4.45 <0.001 1.63 1.15–2.31 0.006 4.42 2.27–8.61 <0.001 1.75 0.84–3.65 0.138
Serum uric acid (per 1 mg/dL increased) 1.16 1.08–1.25 <0.001 1.29 1.14–1.45 <0.001 1.97 1.52–2.55 <0.001 1.34 1.01–1.79 0.042

n: number of subjects; MetS: metabolic syndrome; OR: odds ratio; CI: confidence interval

*

Data adjusted for age, sex, smoking and drinking habits, chronic kidney disease, body mass index and metabolic syndrome category (lean/normal and overweight/obesity with and without metabolic syndrome), and hyperuricemia (or serum uric acid).