Table 1.
Hemodynamic classifications of pulmonary hypertension [4]
| Definition | Characteristicsa | Clinical groups |
|---|---|---|
| PH | PAPm ≥ 25 mmHg | All |
| Pre-capillary PH | PAPm ≥ 25 mmHg | 1. Pulmonary arterial hypertension |
| PAWP ≤ 15 mmHg | 3. PH due to lung diseases | |
| 4. Chronic thromboembolic PH | ||
| 5. PH with unclear and/or multifactorial mechanisms | ||
| Post-capillary PH | PAPm ≥ 25 mmHg | 2. PH due to left heart disease |
| Isolated post-capillary PH (Ipc-PH) | PAWP > 15 mmHg | 5. PH with unclear and/or multifactorial mechanisms |
| Combined post-capillary and pre-capillary PH (Cpc-PH) | DPG < 7 mmHg and/or PVR ≤ 3 WU | |
| DPG ≥ 7 mmHg and/or PVR 3 WU |
a
All values measured at rest. DPG diastolic pressure gradient (diastolic PAP—mean PAWP), PAPm mean pulmonary artery pressure, PAWP pulmonary artery wedge pressure, PH pulmonary hypertension, PVR pulmonary vascular resistance, WU Wood units