Table 1. Summary of PACT efficacy using white light as reported in literature.

Studies	Pathogens	Photosensitizer	Light source	Light fluence	Assay method	Efficacy	Note
Pereira, et al. [41], 2012	E.coli	Cationic- Thiopyridinium ZincPhthalocynine (20µM)	White light (150mW/cm2) Red light (150mW/cm2)	270 J/cm2	Colony counting	105 reduction	Bacterial cells were washed twice with PBS
Alves, et al. [37], 2009.	E.coli and E.faecalis	Cationicmeso- substitutedporphyrin (5µM)	White light (40 W/m2)	64.8 J/cm2	Colony counting	107 reduction	No washing
Wood, et al. [38], 2006	S. mutans deposited biofilm	Erythrosine (22 µM)	White light (22.5mW/cm2)	20.4 J/cm2	To evaluate the clinical plaque disclosing agent erythrosine	102.2 reduction biofilm	200 µm thickness were grown in a constant-depth film fermenter
Paschoal, et al. [39], 2014	S.mutans	Curcumin (7.5 µM) and Toluidine blue (25 µM)	White light (3410mW/cm2)	42 J/cm2	Colony counting	105 reduction	No washing
Marciel, L.,et al. [40] 2017	E.coli and S.aureus	Zn(MeOPy + )8Pc and Tri-Py + -Me-PF (5-10 µM)	White light (150 mW/cm2)	2430 J/cm2	Colony counting	106 reduction	No washing
Rubel et.al [34], 2014	Actinic keratosis	Methyl aminolevulinate	Daylight PDT	22 J/cm2	Lesion treatment	89% lesion treated response rate	Demonstrated the efficacy and safety of DL-PDT vs C-PDT in treating mild facial/scalp AKs.
Neittaanmäki et.al [35], 2014	Actinic keratosis	5-aminolaevulinic acid 5-Methyl aminolevulinate	Daylight PDT and c-PDT	2 hrs a day sun exposure	Lesion treatment	84.5% and 74.2% treated	Compared the efficacy and adverse effect of 5-aminolaevulinicacid (nanoemulsion) with MAL in DL-PDT
Present work	E.coli	Pentalysine Zinc Phthalocynine (10 µM)	White light (12.5 mW/cm2)	4.5 J/cm2	Colony counting	105 reduction