Skip to main content
. 2018 Feb 8;41(5):2755–2763. doi: 10.3892/ijmm.2018.3476

Figure 1.

Figure 1

LMO3 expression is upregulated in GC and closely associated with patient prognoses. mRNA expression levels of LMO3 in (A) 19 gastric tumor (median=1.05, 0.48 to 2.56) and 15 normal gastric tissues (median=3.30, 1.80 to 4.19); and (B) 10 paired gastric tumor (1.629±0.273) and normal tissues (3.038±0.312) within this cohort. **P<0.01. (C) A GC tissue microarray (n=164) indicated that the expression of LMO3 was upregulated in 81.10% of GC tissues. (D and E) Kaplan-Meier analysis of (D) OS (P=0.014) and (E) DFS (P=0.049) for GC patients from the microarray stratified by the expression of LMO3. Scoring of immunohistochemical staining was conducted according to the ratio and intensity of positive-staining cells: 0-35% was designated as a low expression group; >36% was designated as a high expression group. (F and G) Kaplan-Meier plot dataset analysis using the KMplot online tool to determine (F) OS (P<0.001) and (G) DFS (P<0.001) of GC patients stratified by the expression of LMO3 (Affy ID of the dataset, 204424_s_at). The best cutoff value was auto selected using KMplot. DFS, disease-free survival; OS, overall survival; GC, gastric cancer; LMO3, LIM domain only 3.