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. 2018 Feb 20;41(5):2517–2526. doi: 10.3892/ijmm.2018.3506

Figure 2.

Figure 2

Mangiferin attenuates Dex-induced decreases in ALP activity in MC3T3-E1 cells. (A) MC3T3-E1 cells were treated with Dex at the indicated concentrations for 48 h. (B) Prior to exposure to 1 µM Dex for 48 h, MC3T3-E1 cells were pretreated with various concentrations of mangiferin for 3 h. ALP activity was measured at 520 nm using a microplate reader. +P<0.05, ++P<0.01 and +++P<0.001 compared with the control group; ###P<0.001 compared with the Dex treatment group. ALP, alkaline phosphatase; Dex, dexamethasone.