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Mangiferin inhibits Dex-induced oxidative stress in MC3T3-E1 cells. (A) Prior to exposure to 1 µM Dex for 24 h, MC3T3-E1 cells were pretreated with various concentrations of mangiferin for 3 h. (B) Intracellular ROS content was measured by flow cytometry. +++P<0.001 compared with the control group; ##P<0.01 and ###P<0.001 compared with the Dex treatment group. Dex, dexamethasone; ROS, reactive oxygen species.
