Table III.

The clinicopathological characteristics related to miR-23b-3p expression in patients.

Clinicopathological features	N	miR-23b-3p relevant expression (2−ΔCq)			Correlation
		Mean ± SD	t-value	P-value	r-value	P-value
Tissue
Adjacent non-cancerous	101	4.4694±1.99328	−6.847	<0.001	0.46	<0.001
HCC	101	2.7376±1.57739
Age (years)
<50	50	2.7160±1.53973	0.136	0.892	−0.019	0.85
≥50	51	2.7588±1.62852
Sex
Male	80	2.7162±1.55445	−0.265	0.792	0.057	0.568
Female	21	2.8190±1.69930
Cirrhosis
−	54	2.8426±1.53274	−0.715	0.476	0.112	0.256
+	47	2.6170±1.63539
Tumor size
<5 cm	21	2.5905±1.59371	−0.478	0.633	0.067	0.505
≥5 cm	80	2.7762±1.58092
Tumor nodes
Single	57	3.0158±1.45979	2.049	0.043	−0.255	0.01
Multiple	44	2.3773±1.66606
Differentiation
High	7	2.9857±1.65673	F=0.394a	0.675a	−0.044	0.66
Moderate	64	2.8062±1.71722
Low	30	2.5333±1.23995
Clinical TNM stage
I–II	25	3.0520±1.9796	1.151	0.253	−0.192	0.055
III–IV	76	2.6342±1.67766
Metastasis
−	49	3.3959±1.57506	4.435	<0.001	−0.447	<0.001
+	52	2.1173±1.31762
Portal vein tumor embolus
−	69	3.1029±1.60797	3.618	<0.001	−0.34	0.001
+	32	1.9500±1.19055
Tumor capsular infiltration
With complete capsule	49	2.7449±1.60663	0.045	0.964	0.001	0.989
Infiltration or no capsule	52	2.7308±1.56500
Vaso-invasion
−	63	2.9635±1.63917	1.876	0.064	−0.169	0.092
+	38	2.3632±1.41123

^aOne-way analysis of variance (ANOVA) test was utilized; t, Student's t-test; SD, standard deviation; HCC, hepatocellular carcinoma; TNM, tumor node metastasis; ANOVA, analysis of variance.