Table 4.
Characteristics of studies reporting humanistic burden
| Study | Design | Location | Sites/centers | Period | Follow-up | Sample size
|
Age (years), mean ± SD | Female, % | Astigmatism (D), mean ± SD | |
|---|---|---|---|---|---|---|---|---|---|---|
| Eyes | Patients | |||||||||
| Knorz et al43 | Prospective | Europe and South America | Multicenter | NR | 6 months | 88 | 44 | 62.5 | 68.2 | NR |
| Lane et al37 | RCT | USA | Multicenter | NR | 6 months | 62 | 62 | Toric IOL: 69.1±11.9 Spherical IOL: 74.5±9.2 |
50 | NR |
| Mingo-Botín et al38 | Prospective | Spain | Single-center | May 2008–June 2009 | 3 months | 40 | 40 | Toric IOL: 71.5±11.1 Spherical IOL: 75.6±5.9 |
NR | Toric IOL: 1.82±0.37 Spherical IOL: 2.17±1.03 |
| Holland et al39 | RCT | USA | Multicenter | NR | 12 months | NR | 517 | 71 | 55.1 | NR |
| Ahmed et al40 | Single-arm | Canada | Multicenter | NR | 6 months | 240 | 120 | 68±11 | 65.8 | 1.7±0.4 |
| Visser et al41 | RCT | the Netherlands | Multicenter | February 2010–March 2012 | 6 months | 172 | 86 | 74 | 48.8 | Toric IOL: 2.02±0.95 Nontoric IOL: 2±0.84 |
| Mencucci et al42 | Prospective | Italy | NR | NR | 3 months | 120 | 120 | Toric IOL: 73.9±11.4 Monofocal IOL: 77.1±6.7 Control: 75.05±8.7 |
65.8 | Toric IOL: −2.42±0.77 Monofocal IOL: −2±1.07 Control: −0.68±0.24 |
| Supuk et al44 | Single-arm | UK | Multicenter | July 2012–July 2013 | 6 months | NR | 287 | 76.5±6.3 | 55 | NR |
Abbreviations: IOL, intraocular lens; NR, not reported; RCT, randomized controlled trial.