Table 4.

Incidence rate ratio of AKI with modified assumptions: result of sensitivity analysis

Analysis	Incidence rate ratio of AKI in acetaminophen administration period (95% CI)	P	Incidence rate ratio of AKI in washout period (95% CI)	P
Main analysis	1.03 (0.95–1.12)	0.49	1.05 (0.87–1.27)	0.59
Only male (1,124 patients)	1.03 (0.93–1.15)	0.53	1.04 (0.82–1.33)	0.73
Only female (747 patients)	1.01 (0.88–1.16)	0.92	1.05 (0.78–1.42)	0.73
Preceding AKI-affected period
1 day	1.03 (0.95–1.12)	0.49	1.05 (0.87–1.27)	0.59
3 days	1.03 (0.95–1.12)	0.52	1.05 (0.87–1.26)	0.64
14 days	1.03 (0.95–1.12)	0.47	1.07 (0.88–1.29)	0.50
Length of washout period
1 day	1.03 (0.95–1.12)	0.47	1.15 (0.91–1.47)	0.25
7 days	1.02 (0.94–1.11)	0.38	0.94 (0.83–1.07)	0.38
14 days	1.01 (0.93–1.10)	0.76	0.89 (0.80–1.00)	0.05
Including potentially nephrotoxic agents into the model	1.04 (0.96–1.13)	0.36	1.06 (0.88–1.28)	0.55

Abbreviations: AKI, acute kidney injury; CI, confidence interval.