Table 1.

Summary of studies

Author, year	Country	Patient population	Clinical condition(s)	Primary/secondary prevention	Adherence measurement approach
Bansilal et al, 201636	USA	Adults post-myocardial infarction and adults with atherosclerotic disease	Myocardial infarction, atherosclerotic disease	Secondary prevention	Insurance claims data
Bosworth et al, 201721	USA	US military veteran patients in Durham Veterans Affairs Medical Center ambulatory care clinics	Elevated low-density lipoprotein cholesterol	Secondary prevention	Pharmacy refill data, medication possession ratio
Brookhart et al, 200712	USA	Adults who began statin treatment within 12 months	Myocardial infarction and cardiovascular disease	Secondary prevention	Electronic monitor, prescription refill data
Chow et al, 201520	Australia	Ethnically diverse group of adults with varied socioeconomic status	Coronary heart disease	Secondary prevention	6-month follow-up appointments measuring low-density lipoprotein cholesterol, blood pressure, cholesterol, waist circumference, heart rate, total physical activity, and smoking status
Franklin et al, 200633	USA	Patients age 8–18 years	Type 1 diabetes	Secondary prevention	Self-reported data
Gibson et al, 20126	USA	Adults age 18–64 identified with gaps in adherence to statin therapy	Cardiovascular disease	Secondary prevention	Claims data, pharmacy refill data
Huser et al, 20055	USA	Adults prescribed statin therapy	Cardiovascular disease	Secondary prevention	Pharmacy refill data, medication possession ratio
Jackevicius et al, 200211	Canada	Adults 66 and over currently prescribed statins or not prescribed statins	Acute coronary syndrome, coronary artery disease	Separate primary and secondary prevention groups	Claims data, prescription refill data, insurance plan database, hospital discharge database
Johnson et al, 200631	USA	Adults age 21–85 with high cholesterol	High cholesterol	Secondary prevention	Self-reported data
Lauffenburger et al, 201727	USA	Adults 18 or over who began oral hypoglycemic, antihypertensive, or cholesterol medication therapy between 2011 and 2013	Hypoglycemia, hypertension, high cholesterol	Secondary prevention	Insurance claims data
Maciejewski et al, 201437	USA	US military veteran patients from Durham Veterans Affairs Medical Center ambulatory care clinics	Hypertension	Secondary prevention	Self-reported data
Pittman et al, 20118	USA	Adults age 18–61 prescribed statins	Cardiovascular disease	Secondary prevention	Claims data, pharmacy refill data, medication possession ratio
Shaw et al, 201334	USA	Adults age 18 or over recruited from Duke Diet and Fitness Center	Obesity	Secondary prevention	Self-reported data
Vinogradova et al, 20162	UK	Adults age 25–84 without cardiovascular disease and those taking statins	Cardiovascular disease	Separate primary and secondary prevention groups	Pharmacy refill data