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. 2018 Jan 28;22(4):885–894. doi: 10.1016/j.celrep.2017.12.083

Figure 5.

Figure 5

Model for CDKL Protein Ciliary Localization and Potential Roles in Cilium Length Regulation

CDKL proteins localize to the base and/or tip of cilia, and they likely influence IFT (anterograde/retrograde) machinery and/or depolymerizing kinesins to regulate cilium growth and disassembly, respectively, and thus control cilium length.