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. 2017 Nov 3;26(4):1221–1231. doi: 10.1007/s00520-017-3945-8

Table 1.

Patient characteristics

Included patients n = 248 Not included patients n = 40 PAM 1 n = 56 PAM 2 n = 43 PAM 3 n = 104 PAM 4 n = 45 Significance level included patients versus not included patients Significance level PAM groups
Mean [SD] agea 70 [9] 73 [10] 70 [9] 70 [9] 68 [9] 72 [9] .043 .206
Sexb .183 .067
 - Men 85% 77% 75% 84% 89% 91%
 - Women 15% 23% 25% 16% 11% 9%
Having childrenc,d .526 .982
 - No 15% 11% 16% 16% 15% 14%
 - Yes 85% 89% 84% 84% 85% 86%
Living arrangementsc .920 .459
 - Living alone 21% 22% 29% 19% 19% 18%
 - Living together (with partner, children, or in an institution) 79% 78% 71% 81% 81% 82%
Education levele .784 .041
 - Elementary 10% 8% 7% 14% 12% 7%
 - Lower 47% 55% 64% 49% 43% 30%
 - Secondary 25% 23% 18% 26% 24% 36%
 - Higher 18% 15% 11% 12% 22% 27%
Employment status .164 .650
 - Employed in paid work 11% 13% 7% 14% 11% 16%
 - Not employed/not able to work 17% 5% 14% 21% 18% 11%
 - Retired 72% 83% 79% 65% 71% 73%
Smoking statuse .486 .750
 - Is not a smoker 67% 73% 66% 60% 69% 70%
 - Current smoker or quitted smoking 33% 28% 34% 40% 31% 30%
Drinking statuse .302 .269
 - Does not drink 29% 38% 39% 26% 28% 23%
 - Drinks or quitted drinking 71% 62% 61% 74% 72% 77%
Median [range] years since total laryngectomyf 6 [0–34] 11 [0–37] 6 [0–34] 4 [0–27] 5 [0–28] 10 [0–33] .025 .094
Received other treatmentsg .557 .259
 - No 19% 15% 11% 23% 20% 25%
 - Yes, (chemo)radiation 81% 85% 89% 77% 80% 75%
Current speech methodd,g
 - Voice prosthesis 84% 78% 87% 84% 83% 84% .285 .917
 - Injection method 17% 25% 13% 19% 18% 16% .194 .830
 - Electrolarynx 5% 10% 2% 7% 5% 5% .242 NS
 - Other (e.g., cannot speak) 2% 8% 4% 2% 2% 0% .089 NS
Median [range] EQ-5D health status (EQ-5D utility score)h .89 [.07–1.00] 1.00 [.24–1.00] .83 [.07–1.00] .86 [.65–1.00] .90 [.19–1.00] 1.00 [.32–1.00] .297 .004

PAM patient activation measure, SD standard deviation, EQ-5D EuroQol-5 dimensions, NS non-significant

aAge is missing in two patients

bSex is missing in four patients

cHaving children and living situation are missing in seven patients

dMultiple answers possible

eEducation level, smoking status, and drinking status are missing in three patients

fTime since total laryngectomy is missing in 14 patients

gInformation on other received treatments and current speech method is missing in six patients

hEQ-5D health status is missing in nine patients