Table 3.
HRQoL changes grouped per treatment decision
| AS N = 23 |
Curative treatment (RP or RT) N = 38 |
|||
|---|---|---|---|---|
| t0 Mean (SD) |
t1 Mean (SD) |
t0 Mean (SD) |
t1 Mean (SD) |
|
| HRQoL core | ||||
| Global health | 86.4 (15.8) | 87.9 (10.5) | 81.4 (14.4) | 75.0 (18.8) |
| Physical functioning | 93.9 (10.1) | 94.2 (10.7) | 93.3 (13.2) | 92.3 (15.3) |
| Role functioning | 97.0 (9.8) | 97.0 (9.8) | 95.5 (16.0) | 79.7 (29.3)** |
| Emotional functioning | 89.8 (14.5) | 92.0 (13.0) | 85.1 (17.7) | 77.6 (23.7)* |
| Cognitive functioning | 90.5 (13.5) | 92.1 (10.2) | 91.2 (12.1) | 85.5 (20.9)* |
| Social functioning | 93.1 (11.0) | 99.2 (3.6)* | 96.8 (8.6) | 90.5 (18.7)* |
| Fatigue | 10.1 (12.8) | 8.6 (12.8) | 10.5 (16.1) | 21.6 (26.8)** |
| Nausea/vomiting | 3.0 (8.4) | 2.3 (5.9) | 0 (0.0) | 16.5 (2.7) |
| Pain | 5.3 (14.9) | 3.0 (8.4) | 7.0 (14.3) | 15.4 (25.8) |
| Dyspnoea | 7.6 (14.9) | 6.1 (16.7) | 7.9 (19.7) | 8.8 (20.0) |
| Insomnia | 9.1 (15.2) | 6.1 (16.7) | 16.7 (24.2) | 22.8 (31.1) |
| Appetite loss | 4.5 (11.7) | 1.5 (7.1) | 2.6 (9.1) | 8.8 (22.8) |
| Constipation | 1.5 (7.1) | 1.5 (7.1) | 4.4 (13.8) | 13.2 (26.3)* |
| Diarrhea | 3.0 (9.8) | 3.0 (9.8) | 4.4 (11.4) | 11.4 (24.8) |
| Financial difficulties | 0.0 (0.0) | 1.5 (7.1) | 0.9 (5.4) | 3.5 (17.0) |
| Prostate specific | ||||
| Urinary symptoms | 19.3 (12.9) | 14.1 (10.4) | 10.3 (8.7) | 19.0 (18.4)** |
| Bowel symptoms | 2.2 (6.3) | 2.2 (4.5) | 3.1 (5.2) | 8.6 (13.4)* |
| Hormonal symptoms | 3.9 (4.9) | 5.6 (6.7) | 3.0 (4.9) | 6.4 (10.0)* |
| Sexual activity | 60.9 (27.3) | 63.0 (18.1) | 58.6 (20.3) | 68.0 (20.9)* |
| Sexual functioning | 25.0 (17.9) | 23.8 (19.6) | 22.2 (16.4) | 29.6 (18.4) |
All scales are 0–100; for functioning subscales, full functioning is represented by a score of 100; for symptoms, absence of symptoms is represented by a score of 0
AS active surveillance, RP radical prostatectomy, RT radiotherapy
*p < 0.05
**p < 0.01