Table 3.
Variable | Category | Number of patients dentate during follow-up Total n = 51 |
Number of patients edentate during follow-upa
Total n = 5 |
|
---|---|---|---|---|
Demographics | Age, years | Mean (SD) | 59 (8.5) | 62 (5.4) |
Gender | Male/Female | 32/19 | 4/1 | |
Clinical characteristics | Tumor site | Oral cavity | 25 | 1 |
Oropharynx | 26 | 4 | ||
T-classification | T1 | 10 | 1 | |
T2 | 17 | 2 | ||
T3 | 6 | 0 | ||
T4 | 17 | 2 | ||
Not reported | 1 | 0 | ||
N-classification | N0 | 17 | 1 | |
N1 | 7 | 0 | ||
N2 | 25 | 4 | ||
N3 | 1 | 0 | ||
Not reported | 1 | 0 | ||
Cumulative IMRT dose | Median [IQR] | 70 [66–70] | 70 [70–70] | |
Frequency of IMRT | 5/week | 42 | 3 | |
6/week | 9 | 2 | ||
Primary IMRT | 10 | 1 | ||
Postoperative IMRT | 14 | 0 | ||
Primary CHIMRT | 17 | 4 | ||
Postoperative CHIMRT | 10 | 0 | ||
Chemotherapy type | Carboplatin/5-FU | 18 | 4 | |
Cisplatin | 7 | 0 | ||
Cetuximab | 2 | 0 | ||
Wound closure | Primary | 9 | 0 | |
Skin graft/flap | 15 | 0 | ||
Self-reported smoking | Yes/In the past/No/NR | 16/17/17/1 | 4/0/1/0 | |
Alcohol consumption | Yes/No | 40/11 | 3/2 | |
Baseline dental data | Number of teeth | Median [IQR] | 24 [18–27] | 11 [8.5–17] |
Plaque score | Median [IQR] | 50 [25–75] | 70 [45–80] | |
Bleeding score | Median [IQR] | 30 [20–60] | 70 [33–95] | |
PISA | Median [IQR] | 349 [131–863] | 533 [170–1509] | |
DMFS | Median [IQR] | 77 [60–102] | 118 [88–120} |
SD standard deviation, IQR inter quartile range, IMRT intensity modulated radiation therapy, CHIMRT intensity modulated radiation therapy with chemotherapy, DMFS decayed missing filled surfaces. The range of scores is 0–128, NR not reported
aAfter dental screening and pre-radiation treatment of oral foci, five patients needed a full mouth clearance