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. 2017 Apr 27;135(6):570–575. doi: 10.1001/jamaophthalmol.2017.0830

Table 4. Crude and Adjusted Association Between Patient Characteristics and Undiagnosed AMD Status.

Characteristic OR (95% CI) P Value
Crude Age Adjusted
Age 1.06 (1.04-1.09) NA NA
Visual acuity 7.06 (0.78-63.60) 3.94 (0.60-25.81) .15
Visual acuity, logMAR (Snellen)
>0.0 (>20/20) 1.37 (1.01-1.84) 1.23 (0.91-1.65) .17
≤0.0 (≤20/20) 1 [Reference] 1 [Reference] NA
Sex
Male 1.43 (1.5-1.95) 1.39 (1.02-1.91) .04
Female 1 [Reference] 1 [Reference] NA
Race/ethnicity
White, non-Hispanic 1.37 (0.70-2.66) 1.25 (0.64-2.43) .51
Other 1 [Reference] 1 [Reference] NA
General cognitive status
≥24 (Nonimpaired) 1 [Reference] 1 [Reference] NA
<24 (Impaired) 0.50 (0.19-1.32) 0.39 (0.15-1.06) .06
Education level
Less than high school 2.58 (1.08-6.15) 2.40 (1.03-5.62) .04
High school or equivalent 1.38 (0.94-2.03) 1.19 (0.80-1.76) .39
Some college or more 1 [Reference] 1 [Reference] NA
Medical conditions
Hypertension 1.38 (1.02-1.88) 1.32 (0.97-1.80) .08
Heart problems 1.29 (0.94-1.78) 1.19 (0.85-1.65) .31
Circulation problems 1.11 (0.71-1.74) 0.95 (0.59-1.54) .84
Smoking status
Current 0.96 (0.45-2.03) 0.99 (0.47-2.12) .99
Former 1.12 (0.82-1.52) 1.06 (0.78-1.45) .70
Never 1 [Reference] 1 [Reference] NA
AREDS-related nutritional supplement use
Yes 1.01 (0.36-2.84) 1.04 (0.36-2.96) .95
No 1 [Reference] 1 [Reference] NA
Pseudophakia 1.40 (0.95-2.06) 1.11 (0.73-1.68) .62
Family history of AMD 1.33 (0.79-2.23) 1.32 (0.79-2.22) .29
Time since primary care eye examination, mo
<6 1 [Reference] 1 [Reference] NA
6-12 1.20 (0.82-1.73) 1.19 (0.81-1.74) .37
>12 1.03 (0.68-1.55) 0.95 (0.64-1.43) .81
Primary eye care physician type
Ophthalmologist 1 [Reference] 1 [Reference] NA
Optometrist 1.00 (0.72-1.37) 0.99 (0.71-1.36) .94

Abbreviations: AMD, age-related macular degeneration; AREDS, Age-Related Eye Disease Study; NA, not applicable; OR, odd ratio.