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. 2017 Nov 26;42(1):4–19. doi: 10.1002/gepi.22092

Table 1.

Parameters and Notation of Polygenic Model

Design Parameters Interpretation
 n Training sample size
 m Total number of independent markers in genotyping panel
 p 0, p 1 Lower and upper P values to select markers into polygenic score
Genetic model parameters
RGY2
Variance in Y explained by genotypes G; chip heritability of Y
RXY2
Variance in Y explained by environment X
RGX2
Variance in X explained by genotypes G; chip heritability of X
ρ Genetic (chip) correlation between X and Y
π0 Proportion of markers with no effect on Y