Table 2.

Most common causes of bleeding in the neonate

Disseminated intravascular coagulation	Complications of pregnancy (abruption, previa, dead twin, maternal shock) Hypoxia Septicemia (bacterial - - group B strep) (viral - - TORCH) Respiratory distress syndrome. Necrotizing enterocolitis
hemorrhagic disease of the newborn	Vitamin K deficiency
Hereditary bleeding disorders Clotting factors	Hemophilia A and B Other factor deficiencies. AfibrinogenemiaJdysfibrinogenemia Platelets von Willebrand's Hereditary and familial thrombocytopenia Bernard Soulier Syndrome Wiscott Aldrich
Thrombocytopenia	Infections (sepsis, viremia)Intravascular coagulation syndromes s/p exchange transfusion Immune disorders (SLE, ITP, antiplatelet antibodies)
Platelet function defects	Uremia Acidosis Sepsis
Hepatic disease	Hepatitis (TORCH) Alpha-l-antitrypsin deficiency Metabolic defects
Trauma	Child abuse if unexplained