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Effect of enzymes on apical to basolateral transport of mannitol across Caco-2 monolayers. Bars represent average Papp values ± SD (n = 3). The black, dark gray, and light gray bars indicate the presence of no mucin, 100 μL of 50 mg/mL mucin, and 200 μL of 150 mg/mL mucin, respectively. Red, yellow and green regions represent conditions that were not, intermediately and well tolerated. The control was digestion medium.
