Table I.
Name and Composition of Excipients Used in the Investigated Lipid-Based Formulations
| Excipients | Composition |
|---|---|
| Triglycerides | |
| Soybean oil | LC triglycerides: predominantly linoleic acid, linolenic acid, oleic acid, stearic acid and palmitic acid |
| Captex 355 | MC triglycerides: predominantly glycerol tricaprylate (C8)/caprate (C10) |
| Mixed glycerides | |
| Maisine 35–1 | LC glycerides: 33.5% monoglyceride, 50.9% diglyceride and 14.7% triglyceride; predominantly linoleic acid (C18) and oleic acid (C18) |
| Capmul MCM | MC glycerides: 60.7% monoglyceride, 33.1% diglyceride and 4.4% triglyceride predominantly caprylic acid (C8) and capric acid (C10) |
| Surfactants | |
| Cremophor EL | polyethoxylated castor oil (HLB 14–16) |
| Tween 85 | polyoxyethylenesorbitan triolate (HLB 11) |
| Cosolvents | |
| PEG 400 | polyethylene glycol 400 |
| Carbitol | diethylene glycol ethyl ether |
Abbreviations: MC Medium-chain, LC Long-chain