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. Author manuscript; available in PMC: 2018 Mar 12.
Published in final edited form as: J Immunother. 2016 Jun;39(5):205–217. doi: 10.1097/CJI.0000000000000126

Fig. 6. Redirected specificity of T cells for EGFR upon expression of CAR from introduced mRNA.

Fig. 6

(A) Cytokine production of CAR+ T cells was measured by intracellular staining and flow cytometry in CD8+ T cells. Data represented as mean±SD, n=3. (B) Specific cytotoxicity of CAR+ T cells was determined by CRA. Data represented as mean±SD, n=3. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001, two-way ANOVA (Tukey’s post-test).