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. Author manuscript; available in PMC: 2018 Mar 14.
Published in final edited form as: Mol Psychiatry. 2017 Sep 12;23(6):1487–1495. doi: 10.1038/mp.2017.179

Figure 2. Functional characterizations of neurons derived from iPSCs.

Figure 2

A. Neurons derived from unaffected as wells as TD subjects express mature neuronal marker MAP2 and Class III β-tublin.

B. Whole cell currents responses were recorded from human neurons derived from subjects with and without TD;

C. Spontaneous action potentials were recorded from human neurons derived from subjects with and without TD;

D. Synapsin, a synaptic vesicle marker, was detected in human neurons with and without TD.

E. Membrane capacitance, F, Membrane resistance and G, resting membrane potentials of human neurons derived from subjects with and without TD were quantified.