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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Sex Transm Dis. 2018 Apr;45(4):237–242. doi: 10.1097/OLQ.0000000000000741

Table 1.

Characteristics of the syphilis-infected participants (60) involved in this study

Milan (11 participants) Turin (29 participants) Bologna (15 participants) Genoa (5 participants)

Male (N, %) 10 (90.9) 29 (100) 15 (100) 5 (100)
Mean Age (range) 40 (18–70) 36 (20–54) 40.2 (23–67) 33.6 (23–49)

Sexual orientation
 MSM (N, %) 8 (80) 27 (93.1) 13 (86.6) 3 (60)
 Bisexual (N, %) None None 1 (6.6) None
 Heterosexual (N, %) 2 (20) 2 (6.9) 1 (6.6) 2 (40)

HIV status
 Positive (N, %) 3 (27.3) 11 (37.9) 6 (40) 1 (20)
 Negative (N, %) 8 (72.7) 18 (62.1) 9 (60) 4 (80)

Syphilis stage
 Primary (N, %) 7 (63.7) 13 (44.9) 14 (93.4) 4 (80)
 Secondary (N, %) 4 (36.3) 16 (55.1) 1 (6.6) 1 (20)

Lesion location
 Genital (N, %) 7 (63.7) 11 (37.9) 14 (93.4) 4 (80)
 Anal (N, %) 4 (36.3) 10 (34.4) None None
 Oral (N, %) None 6 (20.6) 1 (6.6) None
 Cutaneous (N, %) None 2 (6.9) None 1 (20)

VDRL or RPR median titer (IQR) VDRL, 16 (2–256) VDRL, 8 (4–64)1
RPR, 16 (2–64)2
VDRL, 4 (1–16) All VDRL + No titer available

TPPA or TPHA median titer (IQR) TPHA, 803 TPPA, 640 (80–20480) TPHA, 40 (4–128) TPHA, 5120 (2560–10240)

Neurological/ocular involvement Not determined Absent in all patients Not determined Not determined
1

VDRL was performed on 4 patients of this cohort

2

RPR was performed for 25 patients of this cohort

3

No further dilution was tested