Table 1.
Characteristics of the syphilis-infected participants (60) involved in this study
Milan (11 participants) | Turin (29 participants) | Bologna (15 participants) | Genoa (5 participants) | |
---|---|---|---|---|
| ||||
Male (N, %) | 10 (90.9) | 29 (100) | 15 (100) | 5 (100) |
Mean Age (range) | 40 (18–70) | 36 (20–54) | 40.2 (23–67) | 33.6 (23–49) |
| ||||
Sexual orientation | ||||
MSM (N, %) | 8 (80) | 27 (93.1) | 13 (86.6) | 3 (60) |
Bisexual (N, %) | None | None | 1 (6.6) | None |
Heterosexual (N, %) | 2 (20) | 2 (6.9) | 1 (6.6) | 2 (40) |
| ||||
HIV status | ||||
Positive (N, %) | 3 (27.3) | 11 (37.9) | 6 (40) | 1 (20) |
Negative (N, %) | 8 (72.7) | 18 (62.1) | 9 (60) | 4 (80) |
| ||||
Syphilis stage | ||||
Primary (N, %) | 7 (63.7) | 13 (44.9) | 14 (93.4) | 4 (80) |
Secondary (N, %) | 4 (36.3) | 16 (55.1) | 1 (6.6) | 1 (20) |
| ||||
Lesion location | ||||
Genital (N, %) | 7 (63.7) | 11 (37.9) | 14 (93.4) | 4 (80) |
Anal (N, %) | 4 (36.3) | 10 (34.4) | None | None |
Oral (N, %) | None | 6 (20.6) | 1 (6.6) | None |
Cutaneous (N, %) | None | 2 (6.9) | None | 1 (20) |
| ||||
VDRL or RPR median titer (IQR) | VDRL, 16 (2–256) | VDRL, 8 (4–64)1 RPR, 16 (2–64)2 |
VDRL, 4 (1–16) | All VDRL + No titer available |
| ||||
TPPA or TPHA median titer (IQR) | TPHA, 803 | TPPA, 640 (80–20480) | TPHA, 40 (4–128) | TPHA, 5120 (2560–10240) |
| ||||
Neurological/ocular involvement | Not determined | Absent in all patients | Not determined | Not determined |
VDRL was performed on 4 patients of this cohort
RPR was performed for 25 patients of this cohort
No further dilution was tested