. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: Gastroenterology. 2017 Nov 22;154(4):927–934.e4. doi: 10.1053/j.gastro.2017.11.025

Table 4.

Performance Characteristics of CT Colonography relative to Optical Colonoscopy for detecting adenomas¹^,²^,³

Performance Characteristic	Adenoma Size Category from Optical Colonoscopy
	≥6mm	≥10mm
Patient-Level Analyses⁴
Sensitivity	16/36 44.4 (28.2–60.7)^*	7/10 70.0 (41.6–98.4)
Specificity	193/195 98.9 (97.6–100)	210/221 95.0 (92.2–97.9)
Negative Predictive Value	193/213 90.7 (86.7–94.5)	210/213 98.6 (97.0–100)
Positive Predictive Value	16/18 88.9 (74.4–100)	7/18 38.9 (16.4–61.4)^*

Cell values include number/total number, performance characteristic estimate and two sided 95%-confidence intervals

Optical colonoscopy results are from initial pass before results from virtual colonoscopy were revealed to gastroenterologist. CTC is defined as positive for a patient if at least one ≥6mm lesion as measured by CTC is detected.

Adenomas include serrated polyps

⁴

Adenoma size category represents maximum adenoma size per patient as determined by optical colonoscopy.

-operating characteristics significantly less than 90% (p<.05).