Table 2.

Gestational cytokine concentration in the 2nd and 3rd trimesters and children’s IQ at 7 years (n = 1128)

	Full-scale IQ score		Verbal-scale IQ score		Performance-scale IQ score
	B	99% CI	B	99% CI	B	99% CI
IL-1β	−0.38	−1.13, 0.38	−0.21	−1.05, 0.63	−0.45	−1.29, 0.38
IL-8	0.42	−0.33, 1.17	0.39	−0.45, 1.23	0.38	−0.42, 1.18
IL-6	−0.05	−1.18, 1.07	0.42	−0.74, 1.57	−0.50	−1.82, 0.73
IL-10	−0.28	−1.50, 0.95	0.52	−0.80, 1.84	−1.07	−2.40, 0.26
TNF-α	−2.51	−4.84, −0.18	−1.52	−3.90, 0.85	−3.00	−5.59, −0.38

Models are adjusted for child sex and age, and maternal race, education, age, socioeconomic disadvantage, smoking in pregnancy, history of treatment for psychiatric disorders, body mass index, preeclampsia, and gestational diabetes

Effect sizes are reported per log unit increase in the cumulative cytokine concentration (pg/mL) of each cytokine during gestation

CI confidence interval, IL interleukin, TNF tumor necrosis factor