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. 2018 Mar 12;9(3):392. doi: 10.1038/s41419-018-0395-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — ID8^EV or ID8^hPON2 cells (5 × 10⁶per mouse) were injected subcutaneously in the right flank of C57BL/6J (n = 15 per group). After 5 weeks, mice were sacrificed and tumors were resected and analyzed. a) Tumor weight was measured and expressed in mg. b) Tumor volumes were determined by Vernier calipers measurements (using the formula 1/2 × L × W²) and expressed in mm³. c) Representative tumors from the two groups of mice. Four animals did not develop visible tumors in ID8^hPON2 group. *p < 0.05 compared to ID8^EV-derived tumors