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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Br J Haematol. 2017 Dec 3;180(1):134–146. doi: 10.1111/bjh.15011

Figure 2. Associations between targeted variants in pain-related genes and painful acute VOC episodes or health services utilizations.

Figure 2

(A) and (B) Box and whisker plots showing the association of CACNA2D3-rs6777055 with vaso-occlusive crisis (VOC) (p = 0.025) and with hospitalisation rates (p = 0.008), respectively. (C) and (D). Box and whisker plots showing the association of KCNS1-rs734784 with VOC (p = 0.01) and with hospitalisation rates (p = 0.002), respectively. Conventions are as per Figure 1.