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. 2018 Mar 12;8:4375. doi: 10.1038/s41598-018-22545-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Comparison of representative cyclic voltammogram of Pt microelectrodes in PBS. (B) Charge storage capacity of each microelectrode (n = 5 for each). ANOVA results revealed significant differences (p < 0.01) as compared to circular electrodes (*), and significant differences (p < 0.01) between fractal and serpentine I, serpentine I and serpentine II. (C) Representative impedance spectra of microelectrodes with different shapes The impedance spectra of microelectrodes in PBS. (D) Nyquist plot of microelectrodes (E) Randle’s circuit for equivalent circuit model analysis.