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. 2018 Mar 12;8:4356. doi: 10.1038/s41598-018-21603-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Regional association signals of the previous GWAS risk locus 18q11.2. LocusZoom plot showing the regional association of chr18.19.7-20.75 mb, including the most significant SNP rs35127791 and previous GWAS SNP rs11661542. Purple line indicates the genetic recombination rate (cM/Mb). SNPs in linkage disequilibrium with rs35127791 are shown in color gradient indicating r2 levels (hg19, 1KGP, Nov 2014, EUR).