Table 3.
Exonic and splicing variants of 23 GWAS suggestive genes in 138 FC cases and controls from WES.
| Gene | Loci | Number of tested variants | P-value (SKAT) |
|---|---|---|---|
| ESRRG | 1q41 | 2 | 0.7073712 |
| SLC35F3 | 1q42.2 | 1 | 0.002189217 |
| DTNB | 2p23.3 | 2 | 0.002747022 |
| PLB1 | 2p23.2 | 20 | 0.1122009 |
| PARD3B | 2p33.3 | 13 | 0.9205563 |
| RBMS3 | 3p24.1 | 1 | 0.354907 |
| CCDC80 | 3q13.2 | 8 | 0.0005070405 |
| CPNE4 | 3q22.1 | 1 | 0.7073712 |
| PROM1 | 4p15.32 | 12 | 0.05065522 |
| PDZD2 | 5p13.3 | 19 | 0.7212919 |
| RSPH9 | 6p21.1 | 2 | 0.8510591 |
| CARD11 | 7p22.2 | 4 | 0.8172528 |
| CAMK2B | 7p13 | 3 | 0.09754801 |
| PTPRD | 9p23 | 7 | 0.2814774 |
| PABPC3 | 13q12.13 | 54 | 0.0001097577 |
| RGS6 | 14q24.2 | 1 | 0.7073712 |
| DNAJA4 | 15q25.1 | 2 | 0.5637608 |
| RBFOX1 | 16p13.2 | 5 | 1 |
| CARHSP1 | 16p13.2 | 2 | 0.3250554 |
| ANGPT4 | 20p13 | 4 | 0.09886071 |
| SIRPG | 20p13 | 5 | 0.7073707 |
| HLCS | 21q22.13 | 6 | 0.6115834 |
| SYN3 | 22q12.3 | 3 | 0.5083075 |