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. 2018 Mar 12;200(7):e00622-17. doi: 10.1128/JB.00622-17

TABLE 1.

Functional categories of genes differentially regulated by H2O2a

Gene category No. of genes with:
Increased expression Decreased expression
Amino acid transport and metabolism 26 44
Carbohydrate transport and metabolism 5 15
Cell cycle control, mitosis, and meiosis 2 2
Cell motility 0 2
Cell wall/membrane biogenesis 13 11
Coenzyme transport and metabolism 7 7
Energy production and conversion 32 32
Function unknown 3 4
Hypothetical protein 129 45
Inorganic ion transport and metabolism 16 5
Lipid transport and metabolism 14 12
Nitrogen regulation 1 0
Nucleotide transport and metabolism 7 28
Posttranslational modification, protein turnover, chaperones 17 13
Replication, recombination, and repair 26 9
RNA 0 15
Secondary metabolite biosynthesis, transport, and catabolism 9 4
Secretion 0 8
Signal transduction mechanisms 9 4
Stress 3 0
Toxin 0 1
Transcription 36 11
Translation 3 86
a

Functional gene categories were determined using clusters of orthologous groups. Categories were refined when possible based on reported gene functions.